Hereditary Transthyretin Amyloidosis With Polyneuropthy | Group 1

Inclusion Criteria:

• Satisfy one of the following:
• US Patients: Adult patients (≥ 18 years old) diagnosed with hATTR-PN and prescribed TEGSEDI according to the USPI
• Canadian Patients: Adult patients (≥ 18 years old) diagnosed with stage 1 or stage 2 hATTR PN and prescribed TEGSEDI according to the CPM
• Must have given written informed consent for participation in this study
• Must provide access to their previous medical records
• Are about to initiate or have recently initiated treatment with TEGSEDI and have not received more than 9 doses in total
• Be willing to complete required testing and report any AEs and/or changes in medications
• Satisfy one of the following:
• Females: Non-pregnant and non-lactating; abstinent, or if engaged in sexual relations of childbearing potential, patient is using an acceptable contraceptive method from time of signing the informed consent form (ICF) until 13 weeks after the last dose of TEGSEDI administration
• Males: Abstinent or if engaged in sexual relations with a female of childbearing potential, patient is utilizing an acceptable contraceptive method from the time of signing the ICF until 13 weeks after the last dose of TEGSEDI administration

Exclusion Criteria:

• None