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About HAE

What is HAE?

HAE is a rare and potentially life-threatening genetic disease that causes painful swelling attacks in various parts of the body, mainly in the hands, feet, face, throat, and stomach area. Swelling in the airway can restrict breathing and be fatal. A HAE attack may be triggered by emotional trauma or stress; however, an attack often occurs without a known trigger. Attacks can occur without warning and last up to several days if untreated.

Most cases of HAE are caused by a genetic mutation that affects production of a protein called C1-inhibitor.

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